Building Human-Relevant Immuno Oncology Models: A Conversation With Ncardia’s Sanne Holt

Published on December 12, 2025

When immuno-oncology programs fall short in translation, it is often because the models used upstream do not reflect the biology that developers ultimately care about. That gap is central to the work of Sanne Holt, Associate Director Immuno Oncology at Ncardia. Her role sits at the intersection of assay design, iPSC biology, and the operational realities of drug development.